Wnt signaling pathway

Wnt信号通路是一个复杂的蛋白质作用网络，其功能最常见于胚胎发育和癌症，但也参与成年动物的正常生理过程。如下图所示，现在已发现三种Wnt信号通路，分别是经典Wnt通路（canonical Wnt pathway）、非经典Wnt/平面细胞极化通路（noncanonical Wnt/planar cell polarity pathway，PCP）和非经典Wnt/钙离子通路（noncanonical Wnt/calcium pathway）。所有这三种Wnt信号通路都由Wnt蛋白配体与其受体卷曲受体的结合来激活，将信号传给胞内的散乱蛋白。经典Wnt信号通路参与基因表达的调控，非经典平面细胞极化通路调控细胞骨架控制细胞形状，非经典Wnt/钙离子通路调控细胞内钙离子的浓度。Wnt信号通路常用于临近的细胞之间的通信（旁分泌）或同个细胞自身的通信（自分泌）。Wnt信号通路在动物中高度保守，从果蝇到人类都非常类似。

Target	Antibody	Protein	Clone	ELISA Kit
APC	APC Antibody	APC Protein	APC cDNA	APC ELISA Kit
APC2	APC2 Antibody	APC2 Protein	APC2 cDNA	APC2 ELISA Kit
AXIN1	AXIN1 Antibody	AXIN1 Protein	AXIN1 cDNA	AXIN1 ELISA Kit
AXIN2	AXIN2 Antibody	AXIN2 Protein	AXIN2 cDNA	AXIN2 ELISA Kit
BAMBI	BAMBI Antibody	BAMBI Protein	BAMBI cDNA	BAMBI ELISA Kit
BTRC	BTRC Antibody	BTRC Protein	BTRC cDNA	BTRC ELISA Kit
CACYBP	CACYBP Antibody	CACYBP Protein	CACYBP cDNA	CACYBP ELISA Kit
CAMK2A	CAMK2A Antibody	CAMK2A Protein	CAMK2A cDNA	CAMK2A ELISA Kit
CAMK2B	CAMK2B Antibody	CAMK2B Protein	CAMK2B cDNA	CAMK2B ELISA Kit
CAMK2D	CAMK2D Antibody	CAMK2D Protein	CAMK2D cDNA	CAMK2D ELISA Kit
CAMK2G	CAMK2G Antibody	CAMK2G Protein	CAMK2G cDNA	CAMK2G ELISA Kit
CCND1	CCND1 Antibody	CCND1 Protein	CCND1 cDNA	CCND1 ELISA Kit
CCND2	CCND2 Antibody	CCND2 Protein	CCND2 cDNA	CCND2 ELISA Kit
CCND3	CCND3 Antibody	CCND3 Protein	CCND3 cDNA	CCND3 ELISA Kit
CER1	CER1 Antibody	CER1 Protein	CER1 cDNA	CER1 ELISA Kit
CHD8	CHD8 Antibody	CHD8 Protein	CHD8 cDNA	CHD8 ELISA Kit
CREBBP	CREBBP Antibody	CREBBP Protein	CREBBP cDNA	CREBBP ELISA Kit
CSNK1A1	CSNK1A1 Antibody	CSNK1A1 Protein	CSNK1A1 cDNA	CSNK1A1 ELISA Kit
CSNK1A1L	CSNK1A1L Antibody	CSNK1A1L Protein	CSNK1A1L cDNA	CSNK1A1L ELISA Kit
CSNK2A1	CSNK2A1 Antibody	CSNK2A1 Protein	CSNK2A1 cDNA	CSNK2A1 ELISA Kit